In Crystalline Memories, Vlast talks about a "weapon". He says it has the power to "change the shape the world" and that it was created "so that mortals could do the work of dragons".
It's assume by the player character and team that this weapon Balthazar seeks is the Dragonsblood Spear. The Spear is destroyed without a great deal of ceremony and never mentioned again.
Now, either this is just incredibly poor writing or the weapon being referenced is absolutely not the Spear. It is my thought that the weapon is in fact the Staff of the Mists.
As far as we are aware, the Dragonsblood Spear has absolutely no ability to "change the shape of the world" nor "do the work of dragons". It specifically was designed to combat Kralkatorrik. That's it. The Staff of the Mists however, might.
According the Vissh Rakissh in The Cold Touch of the Past;
The Staff of the Mists contains great power, and allows the wielder to bend the fabric of reality.
The quest occurs just north of The Lair of the Forgotten in GW1 days.
In the following quest, The Hallowed Point, Buuran (the previous spirit "guardian" of the Staff) states:
Long ago, the Staff of the Mists and the Scepter of Orr were given to the great nations of the world as protection. Predictably, those who wielded their power were corrupted. Terrible horrors were unleashed upon the lands once guarded by their benevolent power. The gods themselves were forced to intervene. They struck down both rulers, sealed the scepters within their tombs, and guarded them with powerful magic. With the Staff of the Mists released into the world again, I fear that the forces of evil will not stop until they possess it. Our only choice is to destroy the scepter.
The Staff of the Mists is clearly extremely powerful. He mentions unleashing "terrible horrors" and says that the "Gods were forced to intervene" and seal the Staff away.
Now, with all that in mind, let's look at what Vlast said;
To hold the weapon is to hold the fate of Tyria in your hands - the power to change the shape of the world. Potent enough to fell the Elder Dragons. It's might should not be taken lightly. It was created so mortals could do the work of dragons, of our line. To combat cataclysmic power and prevent the destruction of all life.
Vlast is talking about a weapon that can change the shape of the world, is extremely powerful and do the work of dragons. Compare this to what the Staff of the Mists is said to be capable of. Bending reality, creating horrors and it's extremely powerful. Bending reality and changing the shape of the world sounds pretty similar to me. The work of dragons is a bit vague, but I take this to mean, in a sense, the dragon's "corruption". The Staff of the Mists was used to create "horros", and I'd definitely say that accurately describes what the Dragons create.
Add this to the fact that the staff is located in very, very close proximity to where all these events are taking place and I think you have a compelling case.
The only problem is that the Staff was "destroyed", by throwing it into the Hallowed Point, a pit into the abyss. If you assume the Staff was never really "destroyed" by the player character, I think we may have a reasonable theory.
Would love to hear feedback on this.
Balthazar and Lyssa were doin' it.
Dwayna and Dhuum were doin' it.
Balthazar's Dad was the reason for the human world evacuation.
Abaddon knew about the dragons.
Change my mind.