I'm on Pipewire. After several testing, downgrading and upgrading packages I think my problem is related to Guild Wars 2 recent updates. My other games have zero problem with audio. (Smite, Dawn Of War 3, V-Rising, DOS2, Splitgate, Riftbreaker, Mafia : DE, Hades, Railgrade, New World, PES21, Vampire Survivors, etc)