I have fixed GW2 on my laptop (Ryzen 4800U with integrated GPU)!
My setup:
Newest lutris
Ubuntu 22.04
lutris-GE-Proton7-28-x86_64
DXVK 1.10.3
VKD3D 2.6
Wine 7.18 Staging installed using apt
Env variable in lutris -> VK_ICD_FILENAMES /usr/share/vulkan/icd.d/radeon_icd.i686.json:/usr/share/vulkan/icd.d/radeon_icd.x86_64.json
wine32, wine64 and dxvk were installed using apt (that fixed my problems)
So if anyone has problems with CoherentUI, you can try
sudo apt install wine32 wine64 dxvk