they say it applies to ALL healing over time. for example, it would apply to backpack regenerator, big boomer, Passive healing of healing signet, soothing mist, steadfast rejuvenation and alchemic vigor. There's MANY healing over time effects that sanctuary runes ignored, not just regen. Of course if it was just to gain benefit from regen it would be a severe nerf! Honestly out of everything this is just the most tame change... it just makes it easier to know what works with sanctuary runes now (all healing, simple enough) while potentially making the runes stronger on certain professions with good healing over time effects like engineer...