My game was working last night, but this morning it's done nothing but crash.
Tried removing the local.dat file to rebuild in %appdata% before launching the game, and then replacing it with my original local.dat. This only fixed the issue until I unchecked the DPI scaling option under graphics. This seems to trigger a crash unless you are running the in Windows 8 compatibility mode.
I was also able to get the game to run once this morning with admin mode, but it only worked once. Then back to problems with being sent back to desktop.