How to be unable to interact with anything in gw2, forcing you to ctrl + alt + del into task manager:
Step 1: Activate action camera
Step 2: Get a piece of gear from the inventory or hero ui window and customise it's stats
Step 3: Press on the search bar in the customise stats window, type in it for good measure
Step 4: Press esc (requires esc to close ui windows option on)
And now you can only look at the world around you and the customise window
In this state, the esc key closes the inventory window or hero window from which you selected the item to customise - but the customise window does not prevent action camera from reactivating, meaning you can now look around with your mouse pointer.... and that's all. Press any button and the game will attempt to write in the search bar - you can't esc to close the window, and with no way to open any UI windows (as it will try to type in the search bar instead), the only option is to ctrl/alt/del task manager close gw2 and restart.
/am good at short titles.