I also seem to have this problem since yesterday - I'm from Greece playing on NA for 4 years now, I rarely have latency issues - my average ping is 150 which is fine - no lag. I'm having serrriious trouble though doing the most basic of stuff in pve as well as the OP states. I can't figure out why that is, everything else seems to be working fine, only GW2 lags out a lot. :/