As individual pieces? No, they won't make a huge difference. As a set, they do make some difference IF you are good at playing the class wearing it. There are some advantages, It's account bound so can be shared among any characters using that armor type. I happen to like the classes that wear light armor so it will make sense for me to eventually craft a set for those. Secondly, the stats can be changed for whatever is optimal for the style of play you're using. Need Berserker? Great? Need Viper on a different character? No problem and it's best in class no matter what spec. Finally, you get infusions which make it even better. You can start a set of accesories buy purchasing those for Laurels. Power/Precision/Ferocity are such common stats for competitive builds that it makes sense to get a set of those.